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ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Table of Content

    25 June 2010, Volume 2 Issue 3 Previous Issue    Next Issue
    The shortterm effect observation on the constitutions of children with Qi deficiency or Qi and Yin deficiency after being treated with Naqi Fuqi powder compressed on umbilicus
    WANG Lining,LI Na,ZHANG Xiaochun,et al.
    2010, 2 (3):  197-200. 
    Abstract ( 224 )   PDF (326KB) ( 127 )   Save
    ObjectiveTo observe the shortterm effect of Qi absorption preservation enema on the constitutions of children with Qi deficiency or Qi and Yin deficiency.
    MethodsDivide the 300 cases whose constitutions are Qi deficiency or Qi and Yin deficiency into two groups at random by intervention:one is observation group,the other one is blank control group.The children in observation group were applied with Qi absorption preservation enema.Apply the drug to umbilicus before sleep every night,take the drug off in the morning the second day,once a day;continue using the drug,ten days in one month for three months.The blank control group were given daycare treatment only.Observe all children in the two groups three months later:the scores of physical performance,the change of physical level,the times and the course of respiratory infection.
    ResultsComprared with the blank control group the difference in scores of physical symptom in observation group was statistically significant.Before and after intervention,compare the scores of physical symptom in the observation group,the difference was statistically significant.Before and after intervention,compare the scores of physical symptom in blank control group,the difference was almost not statistically significant,except for the situation of the state of complexion,appetite,enuresis and defecate in the children of Qi deficiency and the situation of the state of complexion,emotional expression in the children of Qi and Yin deficiency.While in observation group,the numbers of respiratory infection were reduced and the course of respiratory infection shortened.
    ConclusionsThe treatment of Qi absorption preservation enema can improve children's state of constitution with Qi deficiency or Qi and Yin deficiency in the short term.
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    Evaluation on clinical efficacy of the treatment of combined internalexternal therapy of traditional Chinese medicine(TCM) for children with pneumonia
    LV Yuxia,HUANG Yang,CHEN Yanyan,et al
    2010, 2 (3):  204-207. 
    Abstract ( 223 )   PDF (534KB) ( 110 )   Save
    ObjectiveTo evaluate the clinical efficacy of combined internalexternal therapy of TCM on children with pneumonia.
    MethodsA total of 236 cases of pneumonia children documented as inpatient were divided into treatment group and control group at random.Besides the basic treatment of western medicine,oral administration of Xiaoerqingfei syrup and Antitussive powder were added to the 120 children in the treatment group and external application of Fuxiong powder were given additionally,while to the 116 children in the control group simulative placeboes were given instead of Fuxiong powder.The body improvement on their clinical symptoms and physical signs were observed after 10 days.
    ResultsThe curedmarkedly effective rates of treatment on disease and syndrome were 95.8% and 94.2% in the treatment group,88.8% and 86.2% in the control group.The days of being in hospital in the treatment group were significantly fewer than the control group.
    ConclusionsCombined internalexternal therapy demonstrates remarkable therapeutic effects on children with pneumonia.
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    〗The effect of prescriptions of Qingre Jiedu and Huayu Tongluo on TNFα and ET1 in MsPGN model rats
    YUN Ying,CAO Guanghai.
    2010, 2 (3):  231-234. 
    Abstract ( 141 )   PDF (546KB) ( 104 )   Save
    Objective〖WT5"BZ〗Observe the effects on TNFα and ET1 expression in renal tissues of rats with mesangial proliferative glomerulonephritis(MsPGN) by Chinese herbs with functions of both the heatclearing and detoxification(HD,Qingre Jiedu),and the removing of blood stasis and channel obstruction(RBSCO,Huayu Tongluo),or each of them,in order to explore mechanism of the Chinese herbs.
    〖WT5"HZ〗Methods〖WT5"BZ〗Male SD rats were included as the study object.The rat models of MsPGN were made by taking orally and timecontrolled vein injecting boving serum albumin(BSA),and vein injecting staphylococcus enterotoxin B(SEB),and spot of division of hypodermic injecting complete Freund's adjuvant and not complete Freund's adjuvant.The proliferation of glomerular mesangial cell(MC) and glomerular extracellular matrix(ECM) was studied by light microscope on rat models of MsPGN,who were treated by combined HD with RBSCO,and by HD,or by RBSCO,respectively.TNFα and ET1 expression in renal tissues was detected by immunohistochemical method,and quantitative analysis was made.
    〖WT5"HZ〗Results〖WT5"BZ〗In the successful mesangial proliferative nephritis models,glomerular mesangial proliferation was mild to moderate,and TNFα and ET1 expression in renal tissues increased significantly(P<0.01).The treatment of combination of HD with RBSCO could significantly reduce TNFα and ET1 expression levels in the renal tissues.HD or RBSCO respectively might have different action mechanism,because HD group was emphased on reducing TNFα expression(P<0.01),while RBSCO Group was emphased on reducing ET1 expression(P<0.01).
    〖WT5"HZ〗Conclusions〖WT5"BZ〗The treatment of combination of HD with RBSCO for MsPGN is more effective than that of single HD or RBSCO,and it can reduce the renal pathological damage through different treatment mechanisms.
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