ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2015, Vol. 7 ›› Issue (5): 480-483.doi: 10.3969/j.issn.1674-3865.2015.05.026

• 临床研究 • 上一篇    下一篇

布拉氏酵母菌预防肠套叠手术复位继发性腹泻临床研究

文海韬   

  1. 410007 长沙,湖南省儿童医院急诊综合外科
  • 出版日期:2015-10-25 发布日期:2015-11-19
  • 作者简介:文海韬(1986-),男,医学硕士,医师。研究方向：小儿外科疾病的诊断与治疗。

Clinical research in Saccharomyces boulardii to prevent secondary diarrhea after surgical reduction for intussusception

WEN Haitao   

  1. Emergency Department of Hunan Children's Hospital, Changsha 410007, China.
  • Online:2015-10-25 Published:2015-11-19

PDF (PC)

810

摘要：
目的：观察布拉氏酵母菌对急性肠套叠患儿手术复位后继发腹泻的治疗效果。
方法：仅仅只是进行(即未行肠修补,肠切除吻合术)急诊肠套叠手术复位的患儿,术后随机分为观察组(术后可进食后即予以布拉氏酵母菌)94例。对照组(术后进食未予以布拉氏酵母菌)88例。入院后所有患儿即查大便常规及隐血、轮状病毒抗原及相关术前检查。术后注意患儿大便性状改变,如有腹泻立即复查大便常规及隐血,复查轮状病毒抗原。
结果：观察组和对照组肠套叠手术后继发腹泻发生率分别为6.3%(6/94)、12.5%(11/88),两组比较差异有统计学意义(χ2=4.63,P=0.03),术后腹泻时间分别为(3.24±1.22)d,(4.63±1.14)d,两组比较差异有统计学意义(F=5.14,P=0.022)。全部患儿均治愈出院,均未发生肠套叠复发、伤口感染、裂开、过敏等情况,出院时大便正常。
结论：微生态制剂布拉氏酵母菌,在急性肠套叠手术复位后继发腹泻的预防方面,有部分疗效,可应用于临床。

关键词: 腹泻, 布拉氏酵母菌/治疗应用, 肠套叠/手术, 复位, 儿童

Abstract:
Objective：To observe the preventive effect of Saccharomyces boulardii on secondary diarrhea after surgical reduction for intussusception.
Methods：The children receiving only emergency operative reduction for intussusception were randomly divided into the observation group (given boulardii) (94 cases)and the control group (no boulardii) (88 cases) after operation.. All of the patients were checked the stool occult blood and rotavirus antigen, and received other preoperative examinations. After operation conditions of the stool were paid attention to,and if diarrhea stool occult blood occurred,we immediately reexamined rotavirus antigen.
Results：In the observation group and the control group the incidence of secondary diarrhea was 6.3% (6/94)and 12.5% (11/88)respectively, the difference between the two groups having statistical significance (χ2=4.63,P=0.03); postoperative time of diarrhea was (3.24±1.22) d and (4.63±1.14)d, the difference between the two groups having statistical significance (F=5.14, P=0.022). All patients were cured and discharged. There was no recurrence of intussusception, wound infection, dehiscence, allergies or other conditions, and the discharge stools were normal.
Conclusion：Saccharomyces boulardii, in terms of the prevention of secondary diarrhea after surgical reduction for intussusception can be applied to treatment.

Key words: diarrhea, Saccharomyces boulardii/treatment application, intussusception/operation, reduction, children

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