ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2020, Vol. 12 ›› Issue (6): 547-.

• 小儿中药应用研究 • 上一篇    下一篇

麻杏石甘汤加减治疗小儿肺炎临床疗效的Meta分析

刘子薇，谢林辰，初航，秦雯，厉妲   

  1. 100094 北京，北京城市学院2016级生物医药专业本科生（刘子薇）；生物医药学部（谢林辰，初航，秦雯，厉妲）
  • 出版日期:2020-12-25 发布日期:2021-05-14
  • 通讯作者: 厉妲，E-mail:lida.lnzyydx@163.com
  • 作者简介:刘子薇(1998)，女，北京城市学院2016级本科生在读。研究方向：Meta分析与卫生技术评估
  • 基金资助:
    北京城市学院优势专业建设项目(yszyjs201702)

A Meta-analysis of the clinical efficacy of the treatment for infantile pneumonia with modified Maxing Shigan decoction

LIU Ziwei，XIE Linchen，CHU Hang，QIN Wen，LI Da   

  1. Beijing City University，Beijing 100094，China
  • Online:2020-12-25 Published:2021-05-14

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摘要： 目的:通过观察麻杏石甘汤加减治疗小儿肺炎的临床疗效进行Meta分析。
方法:使用计算机检索中国生物医学文献数据库(CBM)、中国学术期刊全文数据库(CNKI)、万方数据库、维普数据库、PubMed，搜集以与麻杏石甘汤有关的中药方剂加减治疗小儿肺炎的随机对照试验；采用Cochrane系统评价的方法评价纳入文献的质量，使用Revman 53统计软件对纳入的文献进行Meta分析。
结果:共纳入13个随机对照试验，涉及657例患者，Meta分析结果显示以含有麻杏石甘汤加减的中药方剂治疗小儿肺炎的总有效率优于西药组，合并的OR值为2.31［95%CI(1.82,2.93)］。
结论:以含有麻杏石甘汤加减的中药方剂治疗小儿肺炎急性期的临床疗效较西药有一定优势，且对新型冠状病毒在全球治疗方案中的推广起到了参考依据。

关键词: 肺炎, 麻杏甘石汤, 临床实验, Meta分析, 儿童

Abstract: Objective:To perform a Meta-analysis by observing the clinical efficacy of the treatment for infantile pneumonia with modified Maxing Shigan decoction.
Methods:The Chinese biomedical literature database(CBM), Chinese academic journal full-text database(CNKI), Wanfang database, Weipu database and PubMed were searched by computer to collect the randomized controlled trialsconcerning the treatment for infantile pneumonia with the modified traditional Chinese medicine prescriptions including Maxing Shigan decoction. The quality of included literature was evaluated by Cochrane systematic evaluation method, and the Meta-analysis of included literature was made by Revman 5.3 statistical software.
Results:A total of 13 randomized controlled trials were included, involving 657 patients. The Meta-analysis results showed that the total effective rate of the treatment for infantile pneumonia with Chinese medicine prescription including modified Maxing Shigan decoction was better than that of western medicine, and the combined OR value was 2.31［95%CI(1.82,2.93)］.
Conclusion:Compared with western medicine, the clinical efficacy of Chinese medicine prescriptionsincluding modified Maxing Shigan decoction in the treatment of acute pneumonia in children has certain advantages, and it has provided a reference basis for the promotion of novel coronavirus in the global treatment scheme.

Key words: Pneumonia, Maxing Shigan decoction, Clinical trials, Meta analysis, Child