关键词: 类百日咳综合征, 桑白皮汤, 炎性因子, 肺功能, 儿童

Abstract: Objective: To explore the effect of modified Sangbaipi decoction on children with pertussis-like syndrome.Methods: Forty cases of children withpertussis-like syndrome treated in our hospital from January 2017 to December 2019 were randomly divided into control group(20 cases, treated with azithromycin) and observation group(20 cases, treated with Sangbaipi decoction and azithrpmycin). The total effective rate, inflammatory factor level, pulmonary function index, disappearance time of main symptoms, recovery time of blood routine and hospitalization time were compared between the two groups.Results: The total effective rate of the observation group(95.0%,19/20) was higher than that of the control group(65.0%,13/20)(P<0.05);the respiratory rate of the observation group after treatment was lower than that of the control group, and the tidal volume and inspiration/expiration ratio after treatment were higher than those of the control group(P<0.05); the white blood cell count and C-reactive protein level in the observation group werelower than those in the control group(P<0.05); the disappearance time of main symptoms and the recovery time of blood routine in the observation group were all lower than those in the control group(P<0.05). Compared with thecontrol group, the hospitalization time was shorter(P<0.05).Conclusion: The application of modified Sangbaipi decoction in the treatment of children with pertussis-like syndrome is helpful to enhance the curative effect, improve the lung function, reduce the inflammatory reaction and accelerate the recovery of the disease.

Key words: Pertussis-like syndrome, Sangbaipi decoction, Inflammatory factors, Lung function, Child