ObjectiveTo
investigate the prescription regularity in treating HSP.MethodsThe electronic
medical records of 107 HSP child patients in the Affiliated Hospital of
Shandong University of Traditional Chinese Medicine from May 2016 to September
2020 were collected, and were screened and analyzed which were used to build a
prescription database. Frequency statistics method, association rules and
cluster analysis(K-means
algorithm+regression models) were used to process data mining. Analyze the
prescription regularity of traditional Chinese medicine in treating HSP with
the help of TCMISS(V3.0) The property and flavor, frequency, meridian
distribution, effect and core drug combination of the core drugs were
studied.ResultsThere were 16 Chinese herbs with frequency of usage≥20, and the herbs
with high frequency of usage included: honey-fried licorice root, rhizoma atractylodis, moutan bark, semen coicis,
golden cypress, lithospermum, etc. There were 23 herb pairs with frequency of
usage≥30,and the herb pairs
with high frequency of usage included rhizoma atractylodis-golden cypress,rhizoma atractylodis-moutan bark-semen coicis, moutan
bark-radix paeoniae rubra,
etc. Main taste was bitter and sweet, main drug property was cold, and the main
meridian distribution was in lung, spleen, liver and heart. ConclusionThe
treatment methods for HSP in our hospital were summarized, such as "bitter
and sweet law" and "dispelling latent evil". The main drugs are
to clear away heat and toxic materials and promote blood circulation and remove
blood stasis, and tonifying drugs are used at the same time.