ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2019, Vol. 11 ›› Issue (3): 215-218.doi: 10.3969/j.issn.1674-3865.2019.03.009

• 综述 • 上一篇    下一篇

迷走神经刺激治疗孤独症谱系障碍的研究进展

孙艳秋,罗鑫刚,梁利平,常燕群   

  1. 511400 广州,广东省妇幼保健院康复医学科
  • 出版日期:2019-06-25 发布日期:2019-07-04
  • 通讯作者: 常燕群,E-mail:15246481418@163.com
  • 作者简介:孙艳秋(1990-),女,医学硕士,医师。研究方向:儿童脑发育与行为障碍研究

Research progress in vagus nerve stimulation in the treatment of autism spectrum disorders

SUN Yanqiu,LUO Xingang,LIANG Liping,CHANG Yanqun.   

  1. Department of Rehabilitation Medicine, Guangdong Women and Children's Hospital, Guangzhou 511400, China
  • Online:2019-06-25 Published:2019-07-04

摘要: 孤独症谱系障碍是一种以社会互动、交流交往障碍,异常的重复刻板行为、兴趣范围狭窄及有限和受阻的日常生活活动为临床特征的大脑广泛发育障碍性疾病。因其发病机制不明,目前尚无有效治疗方法。迷走神经刺激以自主神经功能调节为核心,开拓了外周神经大脑网络机体功能整体调节的新原理,已在癫痫共患孤独症谱系障碍、抑郁症以及睡眠障碍等的治疗上取得了较好的治疗作用。本文通过查阅近年来国内外相关文献,概述了经皮迷走神经刺激疗法治疗孤独症谱系障碍的现状及可行性,以期为孤独症谱系障碍儿童的治疗提供新的思路。

关键词: 孤独症谱系障碍, 迷走神经刺激, 治疗方法, 儿童

Abstract: Autism spectrum disorder(ASD) is a widespread developmental disorder of the brain characterized by social interaction and communication disorders, abnormal repetitive stereotyped behavior, narrow range of interest, and limited and obstructed daily activities. Because of its unknown pathogenesis, there is no effective treatment. Vagus nerve stimulation, with autonomic nerve function regulation as its core, opens up a new principle of peripheral nerve-brain network-body function regulation, and has achieved good therapeutic effects in the treatment of epilepsy complicated with autism spectrum disorder, depression and sleep disorder. This article summarizes the current situation and feasibility of vagus nerve stimulation (VNS) in the treatment of autistic spectrum disorder by consulting the related literatures at home and abroad in recent years, in order to provide a new line of thinking about the treatment for autistic spectrum disorder in children.

Key words: Autism spectrum disorders, Vagus nerve stimulation, Treatment, Child