ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2011, Vol. 3 ›› Issue (6): 481-487.doi: 10.3969/j.issn.16743865.2011.06.001

• 专栏 •    下一篇

内服补肾类中药治疗小儿遗尿症的系统评价

孙香娟，常克，张丰华，张玲   

  1. 610072 成都,成都中医药大学附属医院儿科（孙香娟，常克）；610075 成都,成都中医药大学方剂教研室（张丰华）；712046 陕西 咸阳,陕西中医学院儿科（张玲）
  • 出版日期:2011-12-25 上线日期:2019-06-03
  • 通讯作者: 张丰华,610075 成都,成都中医药大学方剂教研室。
  • 作者简介:孙香娟（1978-），女，主治医师。研究方向：小儿肾脏病的诊断与防治。

Systematic evaluation of the treatment for enurisis in children with the kidneynourishing herbs for internal useSUN Xiangjuan, CHANG Ke, ZHANG Fenghua, et al.Department of Pediatrics,Teaching Hospital of Chengdu University of TCM, Chengdu 610072, China

  • Published:2011-12-25 Online:2019-06-03

PDF (PC)

83

摘要：
目的评价内服补肾类中药治疗小儿遗尿症的有效性和安全性，为临床研究提供循证参考。
方法检索内服补肾类中药治疗小儿遗尿症的临床研究文献，对符合纳入标准的研究文献进行质量评价和资料提取。数据采用Cochrane协作网提供的专用软件Revman 4.2进行Meta分析和系统评价，对不能进行Meta分析的数据进行描述性分析，客观评价内服补肾类中药治疗小儿遗尿症的疗效。
结果检出符合纳入标准的文献8篇。纳入文献质量7篇为C级，1篇为B级，Jadad评分为1分的6篇，2分的1篇，4分的1篇。Meta分析结果显示：补肾类中药和行为疗法相结合，则治愈率优于西医组，而好转率两者差异无统计学意义（P＞0.05）；单纯用补肾类中药，治愈率和好转率均与西医组差异无统计意义（P＞0.05）。
结论单纯内服补肾类中药治疗小儿遗尿症疗效不肯定，而与行为疗法相结合治愈率优于西医组；所纳入研究的文献质量不高，为C级和B级证据，有待高质量大样本、多中心的随机对照研究的进一步证实。

关键词: 遗尿症, 中医药疗法, Meta分析, 补肾类中药, 文献计量学, 儿童

Abstract:
ObjectiveTo assess the effect and safety of kidneynourishing herbs for internal use in treatment of enurisis in children, so that clinical treatment decision can be made based on objective believable evaluation of the treatment.MethodsAll the articles about RCT of the kidneynourishing herbs for internal use for enurisis in children were searched for based on the method of evidencebased medicine.The articles that met the inclusion criteria were evaluated by the quality and Jadad scale.Then the data were collected and analysed by Revman 4.2 software.The data were described if they could not be metaanalyzed.So we assessed the efficiency of the internal used herbs for the treatment of enuresis in children.ResultsEight RCTs were included in this review from sixty literatures on controlled studies.The quality of the included studies is seven in C class, one in B class.Jadad scores of 2 points is in one, 4 points in one and 1 in six.Meta analyses showed:the cure rate of the treatment of internal herbs combined with behavior therapy was higher than that of the western medicine.But the upturn rate had no difference.The internal used herbs had no significent differences in the cure rate and upturn rate compared with the western medicine.The treatment of unlimited therapy and period had similar result to that of the internal used herbs.ConclusionsThe effects of the herbs nourishing the kidney for singly internal use are not affirmative.But the cure rate is higher than the western medicine when the herbs are combined with the behavior therapy.The qualities of the included studies are Clevel or Blevel evidence.It needs to be further assessed by highquality, largesample and multicenter RCTs.

Key words: traditional Chinese medicine therapy, treatment application/kidneynourishing herbs, enurisis, children, systematic evaluation