ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2021, Vol. 13 ›› Issue (4): 350-.

• 小儿中药应用研究 • 上一篇    下一篇

加味桔梗汤治疗肺经伏热型儿童过敏性鼻炎临床观察

目的: 观察加味桔梗汤治疗肺经伏热型儿童过敏性鼻炎的临床疗效。
方法: 选取2019年1～12月成都中医药大学附属医院儿科门诊收治过敏性鼻炎患儿101例，随机分为观察组52例和对照组49例。观察组加味桔梗汤治疗，对照组给予开瑞坦治疗，疗程3周。初步评价两组患儿的疗效和安全性。
结果: 治疗3周后观察组鼻炎有效率为92.3%（48/52），显著高于对照组61.2%（30/49），差异有统计学意义（P<0.05）。治疗3周后观察组肺经伏热证候有效率为92.3%（48/52），显著高于对照组79.6%（39/49），差异有统计学意义（P<0.05）。观察组喷嚏、鼻塞、流涕、鼻痒、鼻黏膜肿胀、咽干、咽痒及咽红评分均低于对照组，差异有统计学意义（P<0.05）。两组患儿治疗过程中均未出现不良反应。
结论: 加味桔梗汤治疗后患儿病情得到明显改善，临床疗效显著，且较为安全。   

  1. 610072 成都，成都中医药大学附属医院儿科（孙香娟，于秋香），药剂科（刘莉）；610075 成都，成都秉正堂中医诊所（翁东博）；610075 成都，成都中医药大学方剂教研室（张丰华）
  • 出版日期:2021-08-25 发布日期:2021-12-13
  • 通讯作者: 张丰华，E-mail：hot285@163.com
  • 作者简介:孙香娟（1978-），女，医学博士，副主任医师。研究方向：小儿肾系疾病的防治
  • 基金资助:
    成都中医药大学附属医院科技发展基金（2011-D-YY-24）；成都中医药大学附属医院科技发展基金（Y2019154）

Effects of modified Jiegeng decoction on children with allergic rhinitis with underlying heat in lung meridian

Objective: To observe the clinical efficacy of modified Jiegeng decoction in the treatment of allergic rhinitis in children with underlyingheat of lung meridian.#br# Methods: Totally 101 children with allergic rhinitis treated in the pediatric clinic of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine from January to December 2019 were randomly divided into 52 cases in the observation group and 49 cases in the control group. The observation group was treated with modified Jiegeng decoction, and the control group was treated with Loratadine Tablets for 3 weeks, respectively. Then, the efficacy and safety for the two groups were preliminarily evaluated.#br# Results: After 3 weeks of treatment, the effective rate for rhinitis in the observation group was 92.3% (48/52), which was significantly higher than 61.2%(30/49) in the control group(P<0.05); the effective rate for the syndrome of underlying heat in lung meridian in the observation group was 92.3%(48/52), which was significantly higher than 79.6%(39/49) in the control group(P<0.05). The scores in sneezing, nasalcongestion, runny nose, nasal itching, nasal mucosal swelling, pharyngeal dryness, pharyngeal itching and pharyngeal redness in the observation group were lower than those in the control group(P<0.05). There were no adverse reactions in the two groups.#br# Conclusion: After the treatment of modified Jiegengdecoction, the condition of children with allergic rhinitis has been significantly improved, and the clinical effect is significant and safe.   

  1. The Affiliated Hospital of Chengdu University of TCM, Chengdu 610072，China
  • Online:2021-08-25 Published:2021-12-13

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摘要： 目的: 观察加味桔梗汤治疗肺经伏热型儿童过敏性鼻炎的临床疗效。
方法: 选取2019年1～12月成都中医药大学附属医院儿科门诊收治过敏性鼻炎患儿101例，随机分为观察组52例和对照组49例。观察组加味桔梗汤治疗，对照组给予开瑞坦治疗，疗程3周。初步评价两组患儿的疗效和安全性。
结果: 治疗3周后观察组鼻炎有效率为92.3%（48/52），显著高于对照组61.2%（30/49），差异有统计学意义（P<0.05）。治疗3周后观察组肺经伏热证候有效率为92.3%（48/52），显著高于对照组79.6%（39/49），差异有统计学意义（P<0.05）。观察组喷嚏、鼻塞、流涕、鼻痒、鼻黏膜肿胀、咽干、咽痒及咽红评分均低于对照组，差异有统计学意义（P<0.05）。两组患儿治疗过程中均未出现不良反应。
结论: 加味桔梗汤治疗后患儿病情得到明显改善，临床疗效显著，且较为安全。

关键词: 过敏性鼻炎, 肺经伏热, 加味桔梗汤, 儿童

Abstract: Objective: To observe the clinical efficacy of modified Jiegeng decoction in the treatment of allergic rhinitis in children with underlyingheat of lung meridian.
Methods: Totally 101 children with allergic rhinitis treated in the pediatric clinic of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine from January to December 2019 were randomly divided into 52 cases in the observation group and 49 cases in the control group. The observation group was treated with modified Jiegeng decoction, and the control group was treated with Loratadine Tablets for 3 weeks, respectively. Then, the efficacy and safety for the two groups were preliminarily evaluated.
Results: After 3 weeks of treatment, the effective rate for rhinitis in the observation group was 92.3% (48/52), which was significantly higher than 61.2%(30/49) in the control group(P<0.05); the effective rate for the syndrome of underlying heat in lung meridian in the observation group was 92.3%(48/52), which was significantly higher than 79.6%(39/49) in the control group(P<0.05). The scores in sneezing, nasalcongestion, runny nose, nasal itching, nasal mucosal swelling, pharyngeal dryness, pharyngeal itching and pharyngeal redness in the observation group were lower than those in the control group(P<0.05). There were no adverse reactions in the two groups.
Conclusion: After the treatment of modified Jiegengdecoction, the condition of children with allergic rhinitis has been significantly improved, and the clinical effect is significant and safe.

Key words: Allergic rhinitis, Underlying heat in lung meridian, Modified Jiegeng decoction, Children