ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2021, Vol. 13 ›› Issue (5): 416-420.

• 临床研究 • 上一篇    下一篇

回顾性分析23例百日咳患儿的临床特点

目的:探讨成都地区23例住院百日咳患儿的发病特点及治疗。
方法:回顾性分析2018年1月至2019年12月住院治疗的23例百日咳患儿的临床资料。
结果:所有病例的临床特点：（1）年龄：婴儿15例，幼儿5例，学龄前儿童3例。（2）疫苗接种史：3例未接种，8接种1～2剂，10例接种3剂，2例接种4剂。（3）家庭成员呼吸道感染史：19例有明确的呼吸道症状病例接触史。（4）发病季节分布特点：春季发病7例（30.4%），夏秋各4例（17.4%），冬季8例（34.8%）。（5）实验室检查特点：20例患儿血常规白细胞计数>15×10.9/L，中位值为21.46×10.9/L；合并病原体感染：明确细菌感染5例，明确病毒感染5例；胸部影像学提示肺部感染7例。
结论:成都市冬春季节为百日咳的高发季节；婴幼儿、有呼吸道感染接触史以及未全程接种和及时复种百日咳疫苗的儿童为百日咳的高危人群；高白细胞血症、肺部感染、脏器功能受损为重症百日咳的高危因素。   

  1. 600014 成都，成都市第一人民医院（成都市中西医结合医院）儿科
  • 出版日期:2021-10-25 发布日期:2021-12-06
  • 通讯作者: 邓红波，E-mail：327972417@qq.com
  • 作者简介:唐小利（1985-），女，医学硕士，主治医师。研究方向：儿童呼吸系统疾病与感染性疾病的诊治

Retrospective analysis of the clinical characteristics of 23 children with pertussis

Objective:To investigate the clinical characteristics and treatment of 23 hospitalized children with pertussis in Chengdu.#br# Methods:The clinical data of 23 children with pertussis receiving treatment from January 2018 to December 2019 were retrospectively analyzed.#br# Results:The characteristics of 23 hospitalized children were as follows:（1）Age: there were 15 babies, 5 infants and 3 preschool children.（2）Vaccination history: 3 had none,8 cases had 1 or 2 doses, and 12 had 3 or 4 doses.（3）Respiratory infection history in the family: 19 cases had clear contact history with respiratory symptoms.（4）Season of disease: there were 7 cases(30.4%) in spring,4 in summer(17.4%), 4 in autumn(17.4%) and 8 in winter(34.8%).（5）Laboratory examination: Blood routine examination: Twenty children had WBC≥15×10.9/L, the median value being 21.46×10.9/L; being complicated with other pathogens: 5 cases were infected by the bacteria and 5 cases with respiratory syncytial virus. Chest radiographs showed pulmonary infection in 7 cases.#br# Conclusion:Winter and spring are the high incidence season of pertussis in Chengdu. Infants, the children with a history of contacting with people with respiratory infection and those being not fully vaccinated and being not revaccinated against pertussis in time are at high risk of pertussis.At the same time, hyperleukaemia, pulmonary infection and organ function impairment are the high risk factors for severe pertussis.   

  1. Chengdu Integrated TCM ＆ Western Medicine Hospital，Chengdu 600014，China
  • Online:2021-10-25 Published:2021-12-06

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摘要： 目的:探讨成都地区23例住院百日咳患儿的发病特点及治疗。
方法:回顾性分析2018年1月至2019年12月住院治疗的23例百日咳患儿的临床资料。
结果:所有病例的临床特点：（1）年龄：婴儿15例，幼儿5例，学龄前儿童3例。（2）疫苗接种史：3例未接种，8接种1～2剂，10例接种3剂，2例接种4剂。（3）家庭成员呼吸道感染史：19例有明确的呼吸道症状病例接触史。（4）发病季节分布特点：春季发病7例（30.4%），夏秋各4例（17.4%），冬季8例（34.8%）。（5）实验室检查特点：20例患儿血常规白细胞计数>15×10.9/L，中位值为21.46×10.9/L；合并病原体感染：明确细菌感染5例，明确病毒感染5例；胸部影像学提示肺部感染7例。
结论:成都市冬春季节为百日咳的高发季节；婴幼儿、有呼吸道感染接触史以及未全程接种和及时复种百日咳疫苗的儿童为百日咳的高危人群；高白细胞血症、肺部感染、脏器功能受损为重症百日咳的高危因素。

关键词: 百日咳, 临床特点, 并发症, 儿童

Abstract: Objective:To investigate the clinical characteristics and treatment of 23 hospitalized children with pertussis in Chengdu.
Methods:The clinical data of 23 children with pertussis receiving treatment from January 2018 to December 2019 were retrospectively analyzed.
Results:The characteristics of 23 hospitalized children were as follows:（1）Age: there were 15 babies, 5 infants and 3 preschool children.（2）Vaccination history: 3 had none,8 cases had 1 or 2 doses, and 12 had 3 or 4 doses.（3）Respiratory infection history in the family: 19 cases had clear contact history with respiratory symptoms.（4）Season of disease: there were 7 cases(30.4%) in spring,4 in summer(17.4%), 4 in autumn(17.4%) and 8 in winter(34.8%).（5）Laboratory examination: Blood routine examination: Twenty children had WBC≥15×10.9/L, the median value being 21.46×10.9/L; being complicated with other pathogens: 5 cases were infected by the bacteria and 5 cases with respiratory syncytial virus. Chest radiographs showed pulmonary infection in 7 cases.
Conclusion:Winter and spring are the high incidence season of pertussis in Chengdu. Infants, the children with a history of contacting with people with respiratory infection and those being not fully vaccinated and being not revaccinated against pertussis in time are at high risk of pertussis.At the same time, hyperleukaemia, pulmonary infection and organ function impairment are the high risk factors for severe pertussis.

Key words: Pertussis, Clinical features, Complications, Children