小儿定喘颗粒干预呼吸道合胞病毒肺炎（痰热闭肺证）的临床疗效观察

doi:10.20274/j.cnki.issn.1674-3865.2025.01.019

中国中西医结合儿科学 ›› 2025, Vol. 17 ›› Issue (1): 87-91.doi: 10.20274/j.cnki.issn.1674-3865.2025.01.019

• 小儿中药应用研究 • 上一篇

小儿定喘颗粒干预呼吸道合胞病毒肺炎（痰热闭肺证）的临床疗效观察

李瑞雪，王雪峰，谭春迎，孟斌，张秀英，王辉，李兆洋

110847 沈阳，辽宁中医药大学2022级中医儿科学专业研究生（李瑞雪，王辉，李兆洋）；110032 沈阳，辽宁中医药大学附属医院儿科（王雪峰，张秀英）；110005 沈阳，辽宁省妇幼保健院儿科（谭春迎）；117100 辽宁本溪，本溪满族自治县中医院儿科（孟斌）

收稿日期:2024-12-07 修回日期:2024-12-10 出版日期:2025-02-25 上线日期:2025-02-25
通讯作者: 王雪峰，E-mail：lnzywxf@163.com
基金资助:
国家中医药传承创新中心重点病种项目(2023-247)

Observation on the clinical efficacy of Xiaoer Dingchuan granule in the intervention of respiratory syncytial virus pneumonia(syndrome of phlegm-heat blocking the lung)

LI Ruixue¹,WANG Xuefeng²,TAN Chunying³,MENG Bin⁴,ZHANG Xiuying²,WANG Hui¹,LI Zhaoyang¹

¹Liaoning University of Traditional Chinese Medicine,Shenyang 110847,China；²Affiliated Hospital of Liaoning University of Traditional Chinese Medicine，Shenyang 110032,China；³Liaoning Maternal and Child Health Hospital，Shenyang 110005,China；⁴Benxi Manzu Autonomous County Hospital of Traditional Chinese Medicine，Benxi 117100,China

Received:2024-12-07 Revised:2024-12-10 Published:2025-02-25 Online:2025-02-25
Contact: WANG Xuefeng，E-mail：lnzywxf@163.com
Supported by:
National Traditional Chinese Medicine Inheritance and Innovation Center Key Diseases Project(No.2023-247)

摘要/Abstract

摘要： 目的评价小儿定喘颗粒干预儿童呼吸道合胞病毒肺炎（痰热闭肺证）临床疗效。方法选择2023年6月至2024年6月辽宁中医药大学附属医院、辽宁省妇幼保健院、本溪满族自治县中医院收治住院的呼吸道合胞病毒肺炎（痰热闭肺证）患儿72例为研究对象，随机分为对照组和观察组各36例。对照组采取基础治疗，观察组在对照组治疗的基础上，加用小儿定喘颗粒。治疗7 d后比较两组临床疗效、中医证候疗效、单症缓解时间、消失时间和不良反应。结果治疗后观察组临床疗效、中医证候疗效优于对照组；观察组患儿喘息、咳嗽、喉间痰鸣、发热症状缓解时间少于对照组，差异均有统计学意义（P<0.05）；观察组未发生不良事件。对照组1例，表现为恶心呕吐，经治后消失。结论小儿定喘颗粒在治疗呼吸道合胞病毒肺炎（痰热闭肺证）应用中具有积极的治疗作用，临床疗效较好，加快症状消失时间，临床应用安全性较高，值得临床推广。

关键词: 呼吸道合胞病毒肺炎, 痰热闭肺证, 小儿定喘颗粒, 儿童

Abstract: Objective To evaluate the clinical efficacy of Xiaoer Dingchuan granule in the intervention of respiratory syncytial virus pneumonia (syndrome of phlegm-heat blocking the lung) in children.Methods A total of 72 children with respiratory syncytial virus pneumonia (syndrome of phlegm-heat blocking the lung) admitted to the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Liaoning Maternal and Child Health Hospital and Benxi Manzu Autonomous County Hospital of Traditional Chinese Medicine from June 2023 to June 2024 were selected as the study subjects,who were randomly divided into control group and observation group with 36 cases in each group.The control group received basic treatment,and the observation group received Xiaoer Dingchuan granule in addition to the treatment for the control group.After 7 days of treatment,the clinical efficacy,TCM syndrome efficacy,single symptom remission time,disappearance time and adverse reactions were compared between the two groups.Results After treatment,the clinical effect and TCM syndrome effect of the observation group were better than those of the control group.The remission time of wheezing,cough,gurgling with sputum and fever in the observation group was shorter than that in the control group,and the differences were statistically significant(P<0.05).No adverse events occurred in the observation group.One case in the control group had nausea and vomiting,which disappeared after treatment.Conclusion Xiaoer Dingchuan granule has a positive therapeutic effect in the treatment of respiratory syncytial virus pneumonia (syndrome of phlegm-heat blocking the lung);the clinical effect is good,accelerating the disappearance of symptoms,and clinical application safety is high,which is worthy of clinical promotion.

Key words: Respiratory syncytial virus pneumonia, Syndrome of phlegm-heat blocking the lung, Xiaoer Dingchuan granule, Child

李瑞雪, 王雪峰, 谭春迎, 孟斌, 张秀英, 王辉, 李兆洋. 小儿定喘颗粒干预呼吸道合胞病毒肺炎（痰热闭肺证）的临床疗效观察[J]. 中国中西医结合儿科学, 2025, 17(1): 87-91.

LI Ruixue, WANG Xuefeng, TAN Chunying, MENG Bin, ZHANG Xiuying, WANG Hui, LI Zhaoyang. Observation on the clinical efficacy of Xiaoer Dingchuan granule in the intervention of respiratory syncytial virus pneumonia(syndrome of phlegm-heat blocking the lung)[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2025, 17(1): 87-91.

[1]	李平, 杨凡, 刘瀚旻. 从精准医疗看儿童青少年肥胖治疗的个体化干预策略[J]. 中国中西医结合儿科学, 2025, 17(1): 1-7.
[2]	陈娜, 李连科, 卢以红, 杨洋, 陶琼, 陈竹. 知母-黄柏药对在性早熟中的临床应用研究[J]. 中国中西医结合儿科学, 2025, 17(1): 8-12.
[3]	刘倩楠, 王彦超, 苗艺卓, 李岚. 性早熟的中西医病因研究进展[J]. 中国中西医结合儿科学, 2025, 17(1): 13-16.
[4]	刘子琦, 张桂菊. 饮食结构对儿童性早熟的影响研究现状[J]. 中国中西医结合儿科学, 2025, 17(1): 17-22.
[5]	华智超, 陈玉燕, 杨育访, 陈晓玲. 粪菌移植治疗儿童神经发育障碍性疾病的研究进展[J]. 中国中西医结合儿科学, 2025, 17(1): 22-26.
[6]	王博, 熊磊, 王紫薇, 边际, 杨少颖, 贺喜盈, 明溪. 近20年儿童肺炎临床实践指南及诊疗规范现状分析[J]. 中国中西医结合儿科学, 2025, 17(1): 39-44.
[7]	方艳莹, 甘嘉慧, 徐钰茵, 徐梓莹, 司徒美玲, 余淑娟. 不同年龄段儿童高尿酸血症危险因素分析[J]. 中国中西医结合儿科学, 2025, 17(1): 45-49.
[8]	颜细丽, 刘静, 胡巧梅, 陶玉琼. 百日咳患儿营养不良风险筛查及影响因素分析[J]. 中国中西医结合儿科学, 2025, 17(1): 50-54.
[9]	周敏, 王敏华, 李亚群. 注意缺陷多动障碍心肝火旺证患儿的中医体质分析[J]. 中国中西医结合儿科学, 2025, 17(1): 54-58.
[10]	张瑜, 肖阳, 周梦晓, 孙丽平. 从“食积内热”诊治小儿疾病经验采撷[J]. 中国中西医结合儿科学, 2025, 17(1): 59-63.
[11]	刘旭华, 姜永红. 徐氏潜阳安神法治疗小儿不寐经验[J]. 中国中西医结合儿科学, 2025, 17(1): 63-66.
[12]	崔晨, 李敬伟, 周君慧, 杨楚文, 赵鋆, 蒲晓伟. 小儿鼻鼽从虚从寒论治源流及徐氏儿科扶阳理论的应用浅析[J]. 中国中西医结合儿科学, 2025, 17(1): 67-70.
[13]	陈鸿祥, 李新民, 韩耀巍, 秦潞平. 李新民教授运用疏利三焦法治疗儿童难治性肾病综合征经验[J]. 中国中西医结合儿科学, 2025, 17(1): 71-74.
[14]	魏家璇, 杨见辉, 冯忠发, 李蓉, 赵舜, 刘巧雅. 从“肺主皮毛”理论及“取象比类”方法论治小儿肺系疾病[J]. 中国中西医结合儿科学, 2025, 17(1): 75-78.
[15]	梁朝祺, 隆红艳. 三因制宜在儿童咳嗽变异性哮喘中的应用[J]. 中国中西医结合儿科学, 2025, 17(1): 79-83.

小儿定喘颗粒干预呼吸道合胞病毒肺炎（痰热闭肺证）的临床疗效观察

Observation on the clinical efficacy of Xiaoer Dingchuan granule in the intervention of respiratory syncytial virus pneumonia(syndrome of phlegm-heat blocking the lung)

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价