Table of Content

25 October 2016, Volume 8 Issue 5 Previous Issue    Next Issue

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Current research of traditional Chinese medicine on ADHD in children HAN Xinmin 2016, 8 (5):  465-467.  doi: 10.3969/j.issn.1674-3865.2016.05.001 Abstract ( 600 )   PDF (372KB) ( 226 )   Save In this paper, we analyzed the evolution of TCM name of ADHD, clinical and experimental research, characteristics and advantages，and deficiencies and prospects. Although there are many clinical reports, most of them lack strict design, without multicentric, randomized, controlled and large-sample clinical research. In the recent 10 years, the research projects supported by National Natural Science Foundation of China haven't obtained ground-breaking progress. The advantages of TCM treatment for ADHD are individualized diagnosis and therapy, syndrome differentiation treatment, integral regulation and restoration of the function of the internal organs. In order to make greater innovative achievements, it is necessary to conduct further research and standardize experiment through cooperation. Related Articles | Metrics

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Understanding of ADHD in children based on TCM and the progress of etiology and pathogenesis CHANG Ke 2016, 8 (5):  468-469.  doi: 10.3969/j.issn.167-43865.2016.05.002 Abstract ( 453 )   PDF (267KB) ( 118 )   Save This paper explains and develops characteristics of etiology and pathogenesis about ADHD， which takes traditional Chinese medicine classics as criteria, clinical symptoms for records, the theory of "The balance of Yin-Yang" as the guidance，and the theory of "Three aspects surplus and four aspects insufficiency" as the basis. The excess of Yang，liver and heart causes wind and fire；the insufficiency in spleen，lung and kidney produces phlegm，rheum and damp，and may cause shortage of essence，blood and Yin. The keynote could be summarized as five words：wind，fire，phlegm，stasis and weakness. It could be concluded as follows:wind blows and surges up;fire rises and spirit disturbs;sputum stasis and orifices block;blood-insufficiency in heart and spleen;asthenia of essence and blood;blood stasis refusing Yang. Related Articles | Metrics

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Progress of syndrome differentiation and treatment and application of Chinese patent medicine for children with ADHD WANG Xuefeng 2016, 8 (5):  470-472.  doi: 10.3969/j.issn.1674-3865.2016.05.003 Abstract ( 592 )   PDF (356KB) ( 235 )   Save This paper has teased out the TCM syndrome classification, treatment methods and medication of ADHD in children based on literature. Evidence-based analysis shows all kinds of literature include the following two syndromes：heart and spleen deficiency and internal disturbance syndrome of phlegm fire. The basic rule of treatment is regulating Yin and Yang. The treatment includes these methods：to be relaxed，to nourish kidney and relieve liver， and to tonify spleen and reduce phlegm. Chinese patent medicines for children with ADHD include classic prescriptions, special medicines and other medicines which are based on theory of same treatment for different diseases， all recorded in literature. The classic prescriptions include Zhibo Dihuang pills, Renshen Guipi pills and Baizi Yangxin pills. Special medicines include Xiaoer Huanglong granules and Jingling oral liquid. The other medicines include Changma Xifeng tablets，Xifeng Zhidong tablets and Bushen Jiannao capsules. Most of Chinese patent medicines focus on liver and kidney Yin deficiency and heart and spleen deficiency. The heart and liver fire syndrome and the wind-phlegm syndrome， which are common syndrome types in clinics， have no corresponding Chinese patent medicine. This study can provide guidance for syndrome differentiation, drug selection and further research and development of Chinese patent medicine for ADHD. Related Articles | Metrics

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An exploration on the TCM syndrome distribution and laws of herbs application in children with asthma in acute stage ZHANG Yan,SONG Guihua,LI Jing,GUO Yanrong,GUAN Zhiwei,YU Suping,LYU Weigang,YAO Hongyang,SHI Ji. 2016, 8 (5):  472-475.  doi: 10.3969/j.issn.167-43865.2016.05.004 Abstract ( 572 )   PDF (468KB) ( 160 )   Save Objective：To study the features the distribution of TCM syndrome and laws of herbs application in children with asthma in acute stage. Methods： A total of 161 cases of childhood asthma during attack that met the inclusive criteria were collected;taking its TCM syndromes and herbal prescription as researching points,the features of symdrome distribution of childhood asthma in acute episode and principles of herbs application were explored with SPSS 19.0 statistical software. Results：The top TCM type of childhood asthma in the acute period was febrile asthma,which had a marked difference compared with other tyoes(P＜0.01). When it came to the choice of herbs,Ziwan,Kuandonghua,Chantui,Jiangcan,Sangbaipi,Huajuhong,Juluo,Tinglizi,Chuanbeimu,Zhipipaye,Yuxingcao and Daqingye were the most frequently used ones;concerning categories,the herbs, which could relieve cough or reduce sputum and asthma,clear heat,regulate qi,and calm liver to stop endogenous wind, were most widely used. Conclusion：TCM type of onset-stage childhood asthma is mainly the febrile one; during medication process,the method of clearing heat,transforming phlegm,reducing cough and wheeze should be paid due attention; in addition,herbs which can regulate qi or calm liver to stop endogenous wind should also be used. Related Articles | Metrics

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Effect of low frequency repetitive transcranial magnetic stimulation on gait function and daily life activities of children with spastic cerebral palsy LIU Chen，LI Xiaojie，QI Xunzhong 2016, 8 (5):  476-479.  doi: 10.3969/j.issn.167-3865.2016.05.005 Abstract ( 1122 )   PDF (430KB) ( 135 )   Save Objective：To study the effect of low frequency(1 Hz)repetitive transcranial magnetic stimulation(rTMS) on gait function and daily life activities of children with spastic cerebral palsy. Methods：Forty children treated in hospital or outpatient department with spastic cerebral palsy in Jiamusi University Third Affiliated Hospital from February to December of 2015 were selected and randomly divided into two groups:control group(20 cases) and treatment group(20 cases).Control group received comprehensive rehabilitation treatment，while the treatment group was given comprehensive rehabilitation training and low-frequency repetitive transcranial magnetic stimulation treatment，which lasts a total of 8 weeks.Before and after the treatment footprints analytical method，10 meters walk test(10MWT) and modified Barthel index(MBI) were used to assess the children of the two groups. Results：After 8 weeks of treatment，stride step length and width，10MWT and MBI were improved greatly in the two groups(P<0.01)，and the observation group was better than the control group,the difference being statistical(P<0.01). Conclusion：Low frequency(1 Hz) repetitive transcranial magnetic stimulation combined with comprehensive rehabilitation training can improve the function of walking and daily life activities ability in cerebral palsy children，and its curative effect is better than that of comprehensive rehabilitation training alone. Related Articles | Metrics

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Therapeutic effect of Angong Niuhuang pills on severe hand-foot-mouth disease ZHU Qingxiong,GUAN Wenfang,ZHANG Haiping,ZHU Chunhui,LU Hongchang,LI Subao. 2016, 8 (5):  480-482.  doi: 10.3969/j.issn.167-43865.2016.05.006 Abstract ( 872 )   PDF (338KB) ( 135 )   Save Objective：To observe the effect and side effects of Angong Niuhuang pills on severe hand-foot-mouth disease(HFMD). Methods：Eighty severe HMFD patients who met the inclusion criterion and volunteered to attend the trial were divided into the observation group and the control group randomly,40 patients in each group.The patients in control group were treated with ribavirin,immunoglobulin and symptomatic treatments such as intracranial pressure lowering treatment and defervescence；Angong Niuhuang pills was given for 5 days on the basis of above treatments to the patients in the observation group.The total effective rate，the defervescence time of body temperature,the time needed for sleepiness and myoclonus to disappear and the conversion rate of critically ill patients were compared and analysed. Results：The total effective rate of observation group was significantly higher than that of control group(90.0% vs 72.5%，P<0.05);the defervescence time of body temperature in the observation group was(44.23±10.57)h,which was shorter than that in the control group(56.38±15.83)h，the difference being statistically significant(P<0.05).The time needed for sleepiness to disappear in the observation group was(51.70±7.01)h,which was shorter than that in the control group(60.63±15.11)h，the difference being statistically significant(P<0.05).The time needed for myoclonus to disappear in the observation group was(43.43±8.07)h,which was shorter than that in the control group(50.85±11.90)h，the difference being statistically significant(P<0.05).The conversion rate of critically ill patients in the observation group(0%) was lower in observation group than that in the control group(5%). Conclusion：Treatments with Angong Niuhuang pills in severe HFMD can shorten the defervescence time of body temperature and the time needed for sleepiness and myoclonus to disappear, and reduce the conversion rate of critically ill patients,and it has no intolerable side effects and can be applied to clinical work safely. Related Articles | Metrics

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Individualized nutritional management for children with cerebral palsy LI Suyun,LIU Zhenhuan,JIN Bingxu,LIU Shaolan,LI Nuo,LIANG Biqi 2016, 8 (5):  483-486.  doi: 10.3969/j.issn.167-43865.2016.05.007 Abstract ( 428 )   PDF (474KB) ( 176 )   Save Objective ：To explore the effects of individualized nutritional management on children with cerebral palsy. Methods ：Nutrition management files were set up and the synthetic nutrition was evaluated in 37 children with cerebral palsy,who received individualized intervention for 3 months.Weight-for-length z score(WHZ),length-for-age z score(HAZ)，weight-for-age z score(WAZ),and body mass index-for-age z score(BMIZ) after the intervention were compared with those before the treatment. Results： Among 37 cases,emaciation was in 43% of them,growth retardation 38% and low weight 30%.According to WHZ,all the children were divided into three groups normal nutrition group,mild malnutrition group and moderate-severe malnutrition group.After the individualized nutritional intervention,WHZ(0.4±0.8)and BMIZ(0.6±0.8)in normal nutrition group were significantly improved(P<0.05)；WHZ(-0.8±0.6；-1.5±1.0),WAZ(-1.6±0.9；-2.4±1.0) and BMIZ(-0.7±0.7；-1.1±0.9) in mild malnutrition group and moderate-severe malnutrition group were also improved(P<0.05)。 Conclusion ：There is high incidence of malnutrition in children with cerebral palsy;individualized nutritional management can effectively improve the nutritional status in the short term. Related Articles | Metrics

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Application of Shaoyao Gancao decoction in treatment of pediatric diseases ZHAO Liying 2016, 8 (5):  486-488.  doi: 10.3969/j.issn.167-43865.2016.05.008 Abstract ( 460 )   PDF (406KB) ( 167 )   Save Shaoyao Gancao decoction Department Zhongjing for typhoid mistakenly sweat death,foot spasm syndrome and Yang complex.Professor Wang Lie thinks that Shaoyao Gancao decoction,by harmonizing liver and spleen,has achieved satisfactory effect in the treatment of Tourette syndrome and Yeti disease. In addition,modern pharmacological studies have confirmed that Shaoyao Gancao decoction has obvious sedative,analgesic,anti-inflammatory,antitussive and antiasthmatic effect,relieving striated and smooth muscle spasm and having anti-allergic effects.Therefore,the treatment is effective in children with bronchial asthma,intestinal cramps and urticaria.Professor Wang Lie thinks choosing appropriate medicines according to the theory of traditional Chinese medicine and modern pharmacological research results can improve the curative effect,achieving an excellent results. Related Articles | Metrics

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Discussion on the method of aroma invigorating spleen and infantile anorexia LI Han,XIONG Lei,CHEN Bojun,ZHOU Yingqing,HUANG Yucheng,XU Jun 2016, 8 (5):  489-491.  doi: 10.3969/j.issn.167-43865.2016.05.009 Abstract ( 451 )   PDF (413KB) ( 127 )   Save We analyzed the pathogenic characters of anorexia,illustrated the theoretical basis of the method of aroma invigorating spleen in the treatment of anorexia.We believe that anorexia is caused by incoordination between the spleen and the stomach as well as dysfunction of spleen.Spleen likes being dry and dislikes being wet;spleen disease is often caused by pathogenic dampness,so the method of aroma invigorating spleen is used for appetizing,with the warm and clearing nature of aroma and rising and falling of middle-jiao.The spleen and the stomach are in harmony,turbid dampness removed,functional activity being smooth,and appetite is promoted. Related Articles | Metrics

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Effect of pulmonary surfactant therapy for full-term neonates with acute respiratory distress syndrome ZHANG Xiaochun 2016, 8 (5):  492-494.  doi: 10.3969/j.issn.167-43865.2016.05.010 Abstract ( 374 )   PDF (316KB) ( 99 )   Save Objective:To observe the clinical curative effect of pulmonary surfactant(PS) in the treatment of neonatal acute respiratory distress syndrome(ARDS). Methods:From January 2011 to January 2016,86 patients with ARDS in Loudi Central Hospital were involved in this study,and they were randomly divided into the observation group and the control group with 43 cases in each group.The control group was given mechanical ventilation and conventional drug treatment,while the observation group was given endotracheal intubation with pulmonary surfactant treatment of Poractant Alfa Injection in addition to the treatment for control group,1~7 days as a course.The mechanical ventilation time,oxygen time,respiratory index,oxygenation index and clinical effect of the two groups were observed. Results:The total effective rate of observation group was 90.69%(69.76%,39/43),which was significantly higher than that of control group(30/43),and the difference was statistically significant(P<0.05).In the observation group,mechanical ventilation time,oxygen time,duration of high concentration of oxygen,oxygenation index and respiratory index were more significantly improved compared with those of the control group,the difference being statistically significant(P<0.05).After PS treatment,the incidence of complications was 16.28%(7/43),significantly lower than the control group(44.19%,19/43),and the difference was statistically significant(P<0.05). Conclusion:In the treatment of ARDS early application of PS can effectively improve oxygenation function,greatly shorten the time of mechanical ventilation and oxygen use,and reduce the incidence of ARDS complications,so it is a safe and effective treatment method for a wide range of clinical promotion. Related Articles | Metrics

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Clinical analysis of neonates with cytomegalovirus infection YU Fang，LI Tong 2016, 8 (5):  495-497.  doi: 10.3969/j.issn.167-43865.2016.04.011 Abstract ( 522 )   PDF (341KB) ( 101 )   Save Objective ：To study the clinical features of neonates with cytomegalovirus infection, and to observe clinical effect of ganciclovir(GCV) in the treatment of neonatal cytomegalovirus infection. Methods ：Forty cases of neonates in our hospital with cytomegalovirus infection were collected from January 2011 to October 2015. The patients with multiple organ damage were treated with ganciclovir injection,5 mg/kg per time, once every 12 hours, continuously for 14 days; then 7.5 mg/kg per time，once a day, continuously for 4 weeks. Analyse the clinical features and efficacy. Results ：The 40 neonates were diverse in clinical manifestations, with single or multiple organ damage. The multiple organ damage accounted for 72.5%. Of them, 10 were healed(34.5%), 13 were clearly better(44.8%),5 were better(17.2%),and 1 had no effect. Conclusion ：The clinical manifestations of neonates with cytomegalovirus infection are not special. Education for women of childbearing age, prenatal examination and neonatal screening are important measures in preventing neonates with cytomegalovirus infection. The effect of ganciclovir(GCV) in the treatment of neonatal cytomegalovirus infection is satisfactory. Related Articles | Metrics

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Observation on the curative effect of budesonide in adjuvant treatment of children with acute laryngitis QIAN Chaoying，YU Jianting 2016, 8 (5):  497-499.  doi: 10.3969/j.issn.167-43865.2016.04.012 Abstract ( 517 )   PDF (357KB) ( 89 )   Save Objective：To observe the clinical effect of budesonide in adjuvant treatment of children with acute laryngitis. Methods ：From January 2014 to June 2015, in Pediatric Department of Changshu Hospital of Traditional Chinese Medicine, 120 children with mild and moderate acute laryngitis were selected. According to the admission order, the children were divided into the observation group of 60 cases and the control group of 60 cases. All the cases were given antibiotics and adequate hormone at early stage; both groups were treated with symptomatic and supportive treatment. In addition, the observing group was also given budesonide inhalation. The course of treatment was 5～7 d. Compare the clinical efficacy and the time for hoarseness, barking cough and throat obstruction symptom to disappear. Results： The total effective rate of the observation group was 91.7%(55/60), significantly higher than 76.7%(46/60) of the control group(P<0.05). The time of disappearance of hoarseness, barking cough and throat obstruction symptom was significantly shorter in the observation group than in the control group(P<0.05). No obvious adverse reactions were found in the two groups. Conclusion： Budesonide inhalation has good therapeutic effect on children with acute laryngitis, and it is relatively safe and is worthy of promotion. Related Articles | Metrics

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Clinical observation of complex pulse magnetic therapeutic apparatus in the adjuvant treatment of children with bronchial pneumonia LI Yanyan，CHEN Qiwei，WANG Zhijie 2016, 8 (5):  500-502.  doi: 10.3969/j.issn.167-43865.2016.04.013 Abstract ( 396 )   PDF (351KB) ( 94 )   Save Objective：To observe the clinical efficacy of complex pulse magnetic therapeutic apparatus in the adjuvant treatment of children with bronchial pneumonia. Methods： Collect the data of the hospitalized children with bronchial pneumonia in Pediatric Department of the Second Hospital of Shenyang Medical College between January to December 2015. A total of 218 cases were randomly divided into an observation group(n=112) and a control group(n=106).The conventional treatment was used for the control group, and the conventional treatment combined with complex pulse magnetic therapeutic apparatus(Qd,3～5 d) was used for the observation group. Compare the treatment results and the improvement of clinical symptoms between the two groups. Results： The total effective rate of the observation group was 99.11%(111/112), and the control group was 91.51%(97/106).The difference had statistical significance (P<0.05). There was significantly difference(P<0.05) on improvement time of cough, asthma and moist rales between observation group and control group(P<0.05). The hospitalization time was （5.7±2.5）d in the observation group and （6.9±3.6）d in the control group(P<0.05) with significant difference between two groups(P<0.05). Conclusion：The complex pulse magnetic therapeutic apparatus has a very significant effect on bronchial pneumonia, and can markedly improve the clinical symptoms and shorten the hospitalization time. Related Articles | Metrics

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Analysis of curative effect of Xiyanping injection in the treatment of children with acute upper respiratory tract infection ZHU Lili 2016, 8 (5):  503-505.  doi: 10.3969/j.issn.167-43865.2016.04.014 Abstract ( 521 )   PDF (333KB) ( 124 )   Save Objective ：To observe the clinical effect of Xiyanping injection in the treatment of children with acute upper respiratory tract infection. Methods： A total of 196 children admitted to Sujiatun Central Hospital for acute upper respiratory tract infection between Oct. 2011 to Oct. 2015 were randomly divided into two groups: the control group(98 cases) and the observation group(98 cases).Conventional treatment was given to both groups. In addition, the control group was given ribavirin, while the observation group received Xiyanping injection. The treatment lasted for 3 to 7 days. After treatment, observe the effect, time for cough to improve, time for fever to recede, hospitalization length and adverse reactions in the two groups. Results： The total effective rate of the observation group was 99.0%(97/98), which was better than the control group(90.8%,89/98), the difference being statistical(P<0.05).The observation group was better in cough improvement, fever recession time and hospitalization length than the control group, with statistical difference(P<0.05).There was no adverse reaction in both groups. Conclusion： Xiyanping injection has good effect in the treatment of children with acute upper respiratory tract infection, which can shorten the time of signs and symptoms improvement. It is safe and reliable and is worthy of popularization. Related Articles | Metrics

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Clinical analysis of the liver damage caused by first-time anti-tuberculosis treatment for children with tuberculosis REN Hongmei，YANG Xue，WU Ying，LI Yingchun，TIAN Feifei 2016, 8 (5):  505-508.  doi: 10.3969/j.issn.167-43865.2016.05.015 Abstract ( 562 )   PDF (483KB) ( 191 )   Save Objective：To investigate the risk factors and treatment methods of liver dysfunction due to taking anti-tuberculosis for the first time in children with tuberculosis. Methods：In the children who was admitted to Shenyang Chest Hospital from March of 2008 to May of 2014 and received first-time treatment for tuberculosis(TB) with isoniazid,rifampicin and pyrazinamide,36 developed liver damage within 2 weeks to 3 months of treatment.Fourteen children(38.89%) had the risk factors,among whom 12 children took other drugs at the same time,one had mild malnutrition and one was hepatitis C Virus carrier.The clinical data of the 36 cases were analyzed to summarize the clinical features,treatment protocol and prognosis. Results：All the 36 TB children developed liver damage of different degrees after first-time treatment(23 were acute hepatitis type,5 acute cholestasis type,8 mixed type).After the treatment protocol was adjusted and the drugs that might cause liver damage were stopped(azithromycin,erythromycin,analgesics and antipyretics,cephalosporin,etc.),the 36 children completed the treatment course and were cured. Conclusion：Rifampicin and pyrazinamide are the main drugs that induce liver damage in children receiving treatment for the first time.It may increase the risk of liver damage to use other drugs or if the children have malnutrition or have been with liver diseases before.The drugs should be stopped and give liver-protection treatment for different degrees of damage.Isoniazid,rifapentine,ethambutol and streptomycin can be used in the individualized anti-TB treatment to relieve the patients′ pain and shorten treatment course,in order to cure the disease. Related Articles | Metrics

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Curative effect observation on family training program to improve fine motor ability of the children with cerebral palsy LIN Niannian，MU Yaping，GUO Ling 2016, 8 (5):  509-511.  doi: 10.3969/j.issn.167-43865.2016.05.016 Abstract ( 434 )   PDF (330KB) ( 92 )   Save Objective ：To observe the effect of family training program by the parents under the guidance of therapists in improving the fine motor ability of children with cerebral palsy. Methods：A total of 60 children with different types of cerebral palsy in Liaoning Children′s Hospital from Jan.to Dec.2015 were randomly divided into two groups:the observation group(30 cases) and control group(30 cases).The control group was given routine rehabilitation training,while the parents of the observation group were guided to perform family training program at home by using Peabody Motor Development Scale(2nd edition)(PDMS-2) in addition to the routine training,once a day,30 minutes per time.After 6 months of treatment,compare the effect and the change of fine motor quotient(FMQ) between the two groups. Results：The total effective rate of the observation group was 90.0%(27/30),significantly higher than that of the control group(66.7%,20/30),and the difference was of statistical significance(P<0.05).After treatment,the FMQ of observation group was significantly higher than that of control group,the difference being statistical(P<0.05). Conclusion：The combination treatment of family training performed by parents with the rehabilitation treatment can obviously improve the fine motor ability of children with cerebral palsy. Related Articles | Metrics

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Effect of Chinese medicine orally taken, fumigation and moxibustion in the treatment of children with abdominal-type allergic purpura WEN Yuling，WANG Ying，JIN Fuhou 2016, 8 (5):  512-514.  doi: 10.3969/j.issn.167-43865.2016.04.017 Abstract ( 529 )   PDF (330KB) ( 101 )   Save Objective ：To observe the effect of traditional Chinese medicine orally taken and externally applied in the treatment of abdominal allergic purpura. Methods： Sixty children with abdominal allergic purpura hospitalized in Qiqihaer TCM Hospital from January 2010 to January 2014 were randomly divided into two groups: observation group(30 cases) and control group(30 cases).The control group was given prednisone tablets and Vc pill, while the observation group was given decoction of Chinese medicine, plus feet fumigation with medicinal herbs and moxibustion of abdominal acupoints. The treatment lasted for 2 weeks for both groups. Compare the treatment effect, time length for purpura to disappear and for abdominal pain to be relieved, and the adverse reactions. Results： The total effective rate of the observation group was 100.0%(30/30), significantly higher than the control group（66.7%,20/30）, with statistical difference(P<0.05).Both of the time length were shorter in observation group, and the difference was statistically significant(P<0.05).There was no adverse reactions in both groups. Conclusion： The method of orally taking decoction of Chinese medicine plus feet fumigation with medicinal herbs and moxibustion of abdominal acupoints has great effect in the treatment of children with abdominal allergic purpura, which can remove the purpura and relieve abdominal pain and has fewer adverse reactions. It is very safe and worthy of clinical application. Related Articles | Metrics

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Clinical observation on 86 children with cough and wind-heat syndrome treated with Qingfei and Maxing powder GUAN Yannan,LUO Yan 2016, 8 (5):  514-516.  doi: 10.3969/j.issn.167-43865.2016.05.018 Abstract ( 485 )   PDF (361KB) ( 157 )   Save Objective ：To observe the clinical curative effect of Qingfei and Maxing powder on children with cough and wind-heat syndrome. Methods：Totally 162 cases of children with cough were randomly divided into two groups,the observation group(86 cases) and the control group(76 cases).The treatment group was treated with Qingfei and Maxing powder and the control group with acute bronchitis syrup.The duration of treatment was seven days.The total effective rate of the two groups and the time of fever recession,the time of cough disappearance and the recovery time of signs were observed. Results： The total effective rate was 90.70%(78/86) in the observation group and 78.95%(60/76) in the control group.The therapeutic effect of the observation group was significantly better than that of the control group(P<0.05). Conclusion： Qingfei and Maxing powder can be used in the treatment of children with cough and wind-heat syndrome Related Articles | Metrics

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Diagnosis and treatment of 839 cases of intussusception in children XU Feng，GUO Chunna 2016, 8 (5):  517-519.  doi: 10.3969/j.issn.167-43865.2016.04.019 Abstract ( 984 )   PDF (329KB) ( 214 )   Save Objective ：To study the clinical manifestations and diagnosis and treatment of intussusception in children. Methods： Analysis the clinical data of 839 cases of intussusception in children diagnosed by B ultrasound between Jan. 2013 and Jan. 2016. Results： Among the 839 cases, 599 were male and 240 were female, the ratio of male to female being 2.5∶1. Air enema reduction was successful in 758 cases, the success rate being 90.3%; 81 children were successfully treated by surgery; intussusception relapse occurred in 86 cases, with the recurrence rate being 10.2%, who received air enema reduction again and 85 were successfully treated, the success rate being 98.8%. In the pathological aspect: there were 805 cases of primary intussusception, 34 cases of secondary one(polyps in 5 cases, Meckel's diverticulum in 20 cases, intestinal duplication in 3 cases and allergic purpura in 6 cases). Intestinal necrosis was found in 33 cases during surgery, which was confirmed by pathology after surgery. Conclusion： Air enema reduction is an effective treatment for children with intussusception. Timely surgery is recommended in case of reduction failure in order to avoid intestinal necrosis. For the children with repeated intussusception, there may be the possibility of abnormal anatomy of ileum and cecum and secondary intussusception. Intestinal necrosis is related to the type and length of time of intussusception. Related Articles | Metrics

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Clinical analysis of 172 cases of acute poisoning in children ZHAO Juan,SHAO Donghui 2016, 8 (5):  519-521.  doi: 10.3969/j.issn.167-43865.2016.05.020 Abstract ( 435 )   PDF (362KB) ( 132 )   Save Objective ：To analyze the clinical characteristics acute poisoning in children of poisoning causes,and to seek intervention measures to reduce the occurrence of accidental poisoning. Methods：Analysis the clinical data of 172 children admitted to our hospital for poisoning from Jan.2012 to Mar.2016. Results：172 cases of poisoning mainly pesticides (64,37.21%), followed by drug (47,27.32%); acute poisoning in children,poisoning in 1-3 years old poisoning most (93,54.07%); poisoning by gastrointestinal absorption (157,91.28%); summer season, common, rural children height distribution and prognosis of good. Conclusion：The parents should strengthen the supervision of children, take good care of pesticides and drugs, drugs to understand the basic knowledge, strengthen safety education for children and parents, can reduce the occurrence of poisoning. Related Articles | Metrics

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Analysis of the present situation of serum vitamin A level in 1 490 children aged from 0 to 6 years old in Shenyang LIAO Xin，MU Yaping，LI Fen,WEN Jiangge,LI Na 2016, 8 (5):  522-524.  doi: 10.3969/j.issn.167-43865.2016.05.021 Abstract ( 364 )   PDF (339KB) ( 216 )   Save Objective ：To know about the children vitamin A (VA) level from 0 to 6 years old in Shenyang . Methods：From February 2015 to February 2016,the children aged 0 to 6 were selected as the study subjects.The children were divided into 0 to1 age group,＞1 to 3 age group,＞3 to 6 age group,a total of 1 490,the use of high performance liquid chromatography to detect serum VitA levels. Results：The mean serum VitA level was (1.10±0.26)μmol/L,the incidence of subclinical vitamin A deficiency was 4.0%,and the incidence of suspicious SVAD was 36.6%.The serum VitA level of 0 to 1-year-old children was significantly lower than that of ＞1 to 3-year-old children and ＞3 to 6-year-old children(P<0.05).There was no significant difference in serum VitA between ＞1 to 3-year-old and ＞3 to 6-year-old children(P>0.05).There was no significant difference in the incidence of SVAD and suspicious SVAD among all age groups(P>0.05).The incidence of SVAD in children with diarrhea and respiratory infection was higher than that in healthy children within one month(P<0.01). Conclusion： The prevalence of SVAD and suspicious SVAD in preschool children in our city is still relatively high.It is necessary to raise the awareness of VitA in preschool children and to prevent and intervene the occurrence of vitamin A deficiency in children,especially infants and young children.Thereby fundamentally helping reduce the incidence of respiratory and digestive diseases. Related Articles | Metrics

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Expression of T helper cells in peripheral blood of children with Mycoplasma pneumonia complicated with extrapulmonary manifestations CHEN Xiaogeng，WEI Jiemiao，YAN Hong 2016, 8 (5):  525-527.  doi: 10.3969/j.issn.167-43865.2016.05.022 Abstract ( 499 )   PDF (311KB) ( 111 )   Save Objective ：To analyze the expression level of T helper cells in peripheral blood of children with Mycoplasma pneumonia complicated with extrapulmonary manifestations. Methods： We detected the peripheral T helper cells(CD3+,CD4+,CD8+,CD4+/ CD8+)in the blood of the 97 selected continuous cases of children with Mycoplasma pneumoniae pneumonia before starting treatment,who received treatment in the Children Hospital of Shenyang from Jan.to Dec.2015,and compared with the results of the normal children on the medical conclusions at the same test in the same period(control group,n=35). Results：The expression intensity of the peripheral CD3+,CD4+, and ratio of CD4+ /CD8+ of the Mycoplasma pneumoniae pneumonia group were significantly lower than the control group,while that of CD8+ was higher (P<0.05～ 0.01).In the 97 children with Mycoplasma pneumoniae pneumonia,43 cases had extrapulmonary manifestations(44.33%), and the CD3+level,the CD4+ level,CD4+ /CD8+ ration in the group with extrapulmonary manifestations were obviously lower than the group without extrapulmonary manifestations,while the CD8+ level was higher than the latter(P<0.05～0.01). Conclusion： Peripheral blood helper T cells are abnormally expressed in children with Mycoplasma pneumonia;these abnormalities are more obvious in the patients complicated with extrapulmonary manifestations. Related Articles | Metrics

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Clinical study on antibiotic-associated diarrhea in children SU Yanqi,WANG Dan,JIANG Lin,CAI Hua 2016, 8 (5):  528-530.  doi: 10.3969/j.issn.167-43865.2016.05.023 Abstract ( 389 )   PDF (313KB) ( 123 )   Save Objective ：To analyze the influencing factors of antibiotic-associated diarrhea in children in order to reduce the occurrence of children with AAD. Methods： Analyze 853 cases of infection due to the use of antibiotics in children. According to the occurrence of AAD, divide the cases into AAD group(104 cases) and non-AAD group.Compare the clinical data of the two groups and analyze them statistically. Results： Through research and comparison,the occurrences of AAD were related to the age of the child,the type and the time of use of antibiotics,receiving combination therapy or not, fasting or not,the incidence of primary disease and other factors. Conclusion： Rational use of antibiotics and early intervention therapy will minimize or avoid the occurrence of AAD. Related Articles | Metrics

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Curative effect of calcium dibutyryladenosine cyclophosphate in adjuvant treatment of myocardial damage due to rotavirus enteritis ZHAO Hanqing,SHAO Xinglan 2016, 8 (5):  530-532.  doi: 10.3969/j.issn.167-43865.2016.05.024 Abstract ( 560 )   PDF (353KB) ( 113 )   Save Objective ：To observe the clinical curative effect of calcium dibutyryladenosine cyclophosph-ate in adjuvant treatment myocardial damage due to rotavirus enteritis. Methods： Totally 126 pedeatric patients with rotavirus enteritis who were complicated with myocardial damage were randomly divided into treatment group(63 cases) and control group(63 cases).Both groups were given routine treatment.Based on this，treatment group was treated with calcium dibutyryladenosine cyclophosphate for 7 days. ECG, cardiac enzymes and treatment efficiency were observed. Results：Myocardial enzyme levels in both groups were lower than those before treatment，and the treatment group was lower than control group(P<0.05),and the ECG recovery rates in treatment group(95.83%) was higher than that in control group(92.00%)(P>0.05).The total effective rate of the treatment group(95.24%) was obviously higher than that of the control group(77.78%)(P< 0.05). Conclusion： calcium dibutyryladenosine cyclophosphate have an obvious protective effect on pedeatric rotavirus enteritis complicated with myocardial damage,It provides a good treatment method for the repair of myocardial damage in children. Related Articles | Metrics

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Effect of Xiyanping injection combined with budesonide suspension inhalation on neonatal bronchopneumonia in children WANG Liqiang,TAN Chunying 2016, 8 (5):  533-535.  doi: 10.3969/j.issn.167-43865.2016.05.025 Abstract ( 492 )   PDF (364KB) ( 112 )   Save Objective ：To detect the actual efficacy of treating children′s pneumonia with inhaled budesonide and Xingyanping injection. Methods： Randomly divide 180 children admitted to hospital who where diagnosed with pneumonia into two groups: group A(observation group) and group B(control group).Based on the same conventional therapy in line with national pneumonia diagnosis and treatment path,additionally treat group A with inhaled budesonide and Xiyanping.After one week,compare the treating effects of two groups. Results：The total effective rate was 91.11% and 55.56% in group A and group B,respectively,which was higher in group A than in group B(P<0.05).Group A body temperature recovery time, cough disappearance time rales disappeared time were shorter than group B, the difference was statistically significant (P<0.05). Conclusion： The treatment for children′s pneumonia with additional inhaled budesonide and Xiyanping injection results in higher therapeutic effect and is recommended in clinical use. Related Articles | Metrics

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Study on the relativity of the the related trace elements in serum with 25-(OH)D3 HE Yi,ZHONG Yan,ZHU Sha,DING Dawei 2016, 8 (5):  536-538.  doi: 10.3969/j.issn.167-3865.2016.05.026 Abstract ( 407 )   PDF (272KB) ( 230 )   Save Objective ：To measure the content of 25-(OH)D3(25-hydroxylase catalytic system generated ossification diol) in the blood serum of the children of different ages, and to probe into the relativity of 25-(OH)D3 with BAKP(bone alkaline phosphatase) and trace elements. Methods： Totally 382 cases of children were chosen, who took routine physical examination in the health care center of our hospital, as the research object.Divide the children into 5 groups according to their different ages:≤1，＞1～3，＞3～5，＞5～7 and ＞7～12. Detect the concentration of serum 25-(OH)D3, the serum BAKP and some trace elements, such as the Cu,Zn,Fe and Mg by using enzyme-linked immune testing method. Results： Children of all ages were obviously in lack of 25-(OH)D3.By using the Pearson correlation analysis, it was shown that the relativity between Zn and BAKP,Cu，between Fe and BAKP,Cu,Zn，between Mg and Cu,Z,Fe was very obvious(P<0.05).There was relativity between 25-(OH)D3 and BAKP(P<0.05).But there was no obvious relativity between 25-(OH)D3 and trace elements such as Cu,Zn,Fe and Mg(P>0.05). Conclusion： Children of 0～12 years old have different degree of 25-(OH)D3 deficiency, which is especially serious in the children of 0～3 years old.The relativity analysis shows that there is connection between 25-(OH)D3 and BAKP, but there is no connection between 25-(OH)D3 and such trace elements as Cu,Zn,Fe and Mg.Taking Zn and Fe can help improve the BAKP content,which is very beneficial to children′s health. Related Articles | Metrics

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Clinical observation point injection combined with head acupuncture for children with autism HAO Yongmin,GUAN Chunrong,ZHENG Xueli,PAN Yumei 2016, 8 (5):  539-542.  doi: 10.3969/j.issn.167-43865.2016.05.027 Abstract ( 438 )   PDF (448KB) ( 141 )   Save Objective ：To investigate the effect of point injection of mouse nerve growth factor(mNGF) combined with head acupuncture in treatment of children with autism.  Methods： A total of 59 cases of children with autism aged 24～60 months,were divided into 3 groups according to the time of hospital visit and under the permission of parents:conventional rehabilitation training group(group A,15 cases)，conventional rehabilitation training+head acupuncture group(group B,22 cases);conventional rehabilitation+head acupuncture+point injection group(group C,22 cases).The children were evaluated by ABC and CARS and PPVT scales before and after treatment. Results： ABC score and CARS score were significantly decreased while PPVT score was increased in group B and C,the difference being statistically significant(P<0.05).The treatment effect was better in group C than in group B,the difference being statistically significant(P<0.05). Conclusion： Point injection of mNGF combined with head acupuncture and simple head acupuncture are both effective for 2～5-year old children with autism,but the effect of the former is better than the latter. Related Articles | Metrics

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Clinical psychological nursing care of hospitalized children with infectious diseases ZHANG Hongling 2016, 8 (5):  543-545.  doi: 10.3969/j.issn.167-43865.2016.05.028 Abstract ( 498 )   PDF (372KB) ( 103 )   Save Objective ：To observe and summarize the satisfaction of children in hospital with infectious diseases who received psychological nursing intervention. Methods：Totally 74 hospitalized children with infectious diseases were chosen as the observation subjects,and they were divided into observation group(37 cases) and control group(37 cases) according to random table method.Both groups were given conventional treatment and nursing care for infectious diseases,and the children in observation group received psychological nursing intervention based on the different characters of children;meanwhile,the parents were given some psychological health education.The satisfaction was investigated in the two groups when the children were discharged from hospital. Results： The satisfaction of the observation group was better than that of the control group,and the difference was statistical(P<0.05). Conclusion： It will make the children happy to strengthen psychological nursing intervention while providing treatment for infectious diseases,which is beneficial to the recovery of children. Related Articles | Metrics

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Professor Qin Yanhong′s experience in the treatment of infantile diarrhea of spleen deficiency LU Junping,QIN Yanhong，SHI Huijuan 2016, 8 (5):  545-547.  doi: 10.3969/j.issn.167-43865.2016.05.029 Abstract ( 431 )   PDF (440KB) ( 117 )   Save This paper introduces professor Qin Yanhong's clinical experience in the treatment of infantile diarrhea with spleen deficiency. Teacher according to the physiological and pathological characteristics of children with "Spleen Deficiency" and her years' of clinical experience in pediatrics Prof. Qin used her self-made prescription "yunhuang powder" in combination with acupoint paste application and magnetic therapy of Tianshu acupoint to treat spleen deficiency in children ;meanwhile, Prof. Qin has paid a lot of attention to prevention and regulation, which has brough about satisfactory effect. Related Articles | Metrics

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The study of Professor Cui Wencheng's  experience in treating infantile  anaphylactic cough and gasp(syndrome of yin-deficiency and phlegm retention) HAO Yunping，CUI Wencheng 2016, 8 (5):  548-549.  doi: 10.3969/j.issn.167-43865.2016.05.030 Abstract ( 429 )   PDF (256KB) ( 114 )   Save Infantile anaphylactic cough and gasp，syndrome of yin-deficiency and phlegm retention，is characterized by repeated dry cough and less phlegm,which is more significant during the night or in the early morning.It is often caused by exposure to allergen or irritating smell,and is more serious at movement.The tongue is red with less fur or lingua geographica,and the pulse is weak.Pro.Cui Wencheng often uses the Shenmai Huayin recipe in the treatment of the syndrome based on the theory of nourishing yin,eliminating phlegm and relieving cough. Related Articles | Metrics

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Chief Physician Jia Liujin's treatment for children with hybrocele through tonifying method and resolving method SHI Huijuan，QIN Yanhong，LI Mengjiao，LU Junping 2016, 8 (5):  550-551.  doi: 10.3969/j.issn.167-43865.2016.04.031 Abstract ( 481 )   PDF (269KB) ( 125 )   Save Hybrocele of children is a common diseases of urinary system，which reflects the water metabolism of human body. In western medicine surgery is the main way of treatment, which causes some pain to children. Traditional Chinese medicine has the advantage of low cost, obvious treatment effect and being easily accepted by children. Chief Physician Jia Liujin thinks that etiology and pathogenesis of hybrocele is spleen and kidney deficiency, cold coagulation and liver depression, and rheumatic attack. As for treatment, he focuses on inducing diuresis and excreting dampness, taking the method of tonifying spleen and kidney, eliminating cold and stopping pain at the same time. Satisfactory clinical effect has often been obtained. Related Articles | Metrics

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Analysis of the etiology and pathogenesis of obesity in children based on the theory of five internal organs LIU Lirong，ZHANG Guiju，CHEN Fengling，FENG Qiuzhu，YU Ke 2016, 8 (5):  552-554.  doi: 10.3969/j.issn.167-43865.2016.04.032 Abstract ( 366 )   PDF (394KB) ( 116 )   Save Based on the physiological features of five internal organs of children and through combination of ancient theory with modern dieting and living habits of children, the relationship between obesity in children and five internal organs was analyzed. The five internal organs of children have the following features: kidney being deficient, spleen and lung being not sufficient, and liver and heart being enough to spare. The key to the pathognesis of child obesity is that the spleen doesn't function properly and the liver Qi is stagnated. The lesion is mainly in the liver and spleen, and is closely related to the kidney. Also, it is associated with heart and lung dysfunction. The pathological products are sputum accumulation, edema and blood stasis. Mean while, obesity has effect on the five internal organs and causes some related diseases. Therefore, in the treatment of obesity, we should pay attention to the physiques of children and emphasize the concept of integrity and syndrome differentiation. Related Articles | Metrics

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Study on serum vitamin A levels of children aged 0-14 years in Shenyang WANG Yanhua,LIAO Xin 2016, 8 (5):  554-556.  doi: 10.3969/j.issn.167-43865.2016.05.033 Abstract ( 335 )   PDF (370KB) ( 191 )   Save Objective ：To have a general idea of the level of serum vitamin A and its deficiency in children in Shenyang area. Methods： All blood samples of 1 636 children(aged 0-14 years old) in Shen yang Children′s Hospital from January 2015 to February 2016 were selected and divided into groups by sex and age to analyze vitamin A levels and to evaluate the deficiency. Results：There was no significant difference in VitA mean value among different age groups,and it was increased with age.A very small proportion of each age group had a real lack of serum vitamin A,but ratio of marginal lack should not be overlooked. Conclusion：Marginal vitamin deficiency is more common in children in Shenyang area,so balanced nutrition should be advocated and regular monitoring should be performed. Related Articles | Metrics